The Epilepsy Foundation Eastern Pennsylvania was founded in 1972 by local families and a neurologist who saw the need for information and support beyond the medical aspects of the disorder.  Incorporated as the Epilepsy Foundation of Philadelphia, the name was changed in 1992 to the Epilepsy Foundation of Southeastern Pennsylvania to reflect the eleven-county area served by the foundation.  In 2001, through the foundation's national office and the Pennsylvania Department of Health, the organization's name was changed again to expand our service territory into the seven counties representing the northeastern region of Pennsylvania.

The foundation continues to be the only organization in this region established to specfically address the non-medical needs of those with epilepsy/seizure disorder and their families.

The foundation is an independently incorporated affiliate of the Epilepsy Foundation National Office in Landover, Maryland.

The foundation's main office is located in Center City Philadelphia with a field office at the Kirby Health Center in Wilkes-Barre and a staff person in the Lehigh Valley.